Case of Subcutaneous Nodules for Diagnosis

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Subcutaneous Rheumatoid Nodules.

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Subcutaneous rheumatoid nodules.

We describe seven children with subcutaneous rheumatoid nodules who had no clinical evidence of rheumatoid arthritis. Only one girl was seropositive for antinuclear factors and had a slightly raised erythrocyte sedimentation rate. Clinical aspects, risks for developing rheumatoid arthritis, and treatment of this entity are discussed.

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Subcutaneous nodules of Still's disease.

The observations of Collins (1937) and of Bennett, Zeller, and Bauer (1940) established clearly the pathological differentiation of the ordinary subcutaneous nodules in rheumatic fever and in rheumatoid arthritis. In brief, the rheumatic fever nodule is characterized by much fibrinoid material arranged in a lattice with apparently clear spaces between the strands, considerable oedema, but relat...

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Immunopathology of subcutaneous rheumatoid nodules.

Nodules obtained from five patients with classical seropositive rheumatoid arthritis were studied by an immunofluorescence technique using polyclonal antibodies to IgG, IgA, IgM, C3c, and fibrin, and monoclonal antibodies to the terminal (C5b-9) complement complex (reaction with a neoantigen in C9 revealed during activation), DR antigens, T cells, macrophages, and interdigitating cells. In all ...

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Subcutaneous nodules in rheumatoid arthritis.

A 29 year old male with rheumatoid arthritis (RA) of 10 years duration presented with multiple subcutaneous nodules of one month duration while on methotrexate (7.5 mg once a week), salazopyrine (1000 mg/day) and methyl prednisolone (4 mg/day). The nodules involved tendons of metacarpophalangeal joints (Figure 1) and base of left great toe (Figure 2), were painless and did not interfere with hi...

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ژورنال

عنوان ژورنال: Proceedings of the Royal Society of Medicine

سال: 1925

ISSN: 0035-9157

DOI: 10.1177/003591572501800369